Bioactive Small Molecules
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Filtered Search Results
Apexbio Technology LLC A922500, 5mg. Cas: 959122-11-3 MFCD: MFCD12828780. DGAT-1 inhibitor
A922500 is a potent, active, selective and orally bioavailable inhibitor of diacylglycerol acyltransferase-1 (DGAT-1). It is a small molecular with the formula of C26H24N2O4 and molecular weight of 428.48. Other sizes are available. Please inqury us for quote.
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Apexbio Technology LLC HATU, 25g. Cas: 148893-10-1 MFCD: MFCD00274639. used in peptide coupling chemistry
HATU(1-[Bis(dimethylamino)methylene]-1H-1,2,3-triazolo[4,5-b]pyridinium 3-oxid hexafluorophosphate) is a reagent used inpeptide couplingchemistry to generate an active ester from a carboxylic acid. Other sizes are available. Please inqury us for quote.
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Apexbio Technology LLC Celastrol, 5mg. Cas: 34157-83-0 MFCD: MFCD03424073. Antioxidant, anti-inflammatory and immunosuppressive agent
Celastrol is a potent proteasome inhibitor [1].Proteasomes are protein complexes that degrading unneeded or damaged proteins by proteolysis.Celastrol is a potent proteasome inhibitor and an antioxidant, anti-inflammatory and immunosuppressive agent. Other sizes are available. Please inqury us for quote.
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Selleck Chemical LLC Ixazomib Citrate MLN9708-5mg
Ixazomib citrate (MLN9708, Ninlaro) is a prodrug of Ixazomib (MLN2238), which is a selective, orally bioavailable inhibitor of 20S proteasome that inhibits the chymotrypsin-like proteolytic (β5) site with IC50 of 3.4 nM and Ki of 0.93 nM, respectively. Ixazomib (MLN2238) also inhibits caspase-like (β1) and trypsin-like (β2) proteolytic sites with IC50 of 31 nM and 3500 nM, respectively.
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EVIDENT SCIENTIFIC MIS INC
NC3997966 STAGE EXTENSION PLATE FOR CK2
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STEMCELL Technologies A 83-01, Size: 10 mg
Inhibit activin receptor-like kinase (ALK), including ALK5 (type I transforming growth factor-β receptor), ALK4 (type IB activin receptor), and ALK7 (type I NODAL receptor) with A 83-01 (Tojo et al. Cancer Sci, 2005). A 83-01 inhibits mesoderm and endoderm specification (Zhang et al. Cell Stem Cell, 2016), facilitates the conversion of epiblast stem cells to the naїve pluripotent state (Zhou et al. J Biol Chem, 2010; Li et al. Cell Stem Cell, 2009), and disrupts epithelial to mesenchymal transition through inhibition of the SMAD signaling pathway (Tojo et al. Cancer Sci, 2005). In combination with PD0325901, A 83-01 also enables OCT4-mediated reprogramming (Zhu et al. Cell Stem Cell, 2010). A 83-01 is supplied as a crystalline solid with ≥ 95% purity; Molecular weight 421.5 g/mol; CAS number 909910-43-6. Visit STEMCELL.com for more information and related products.
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STEMCELL Technologies A 83-01, Size: 5 mg
Inhibit activin receptor-like kinase (ALK), including ALK5 (type I transforming growth factor-β receptor), ALK4 (type IB activin receptor), and ALK7 (type I NODAL receptor) with A 83-01 (Tojo et al. Cancer Sci, 2005). A 83-01 inhibits mesoderm and endoderm specification (Zhang et al. Cell Stem Cell, 2016), facilitates the conversion of epiblast stem cells to the naїve pluripotent state (Zhou et al. J Biol Chem, 2010; Li et al. Cell Stem Cell, 2009), and disrupts epithelial to mesenchymal transition through inhibition of the SMAD signaling pathway (Tojo et al. Cancer Sci, 2005). In combination with PD0325901, A 83-01 also enables OCT4-mediated reprogramming (Zhu et al. Cell Stem Cell, 2010). A 83-01 is supplied as a crystalline solid with ≥ 95% purity; Molecular weight 421.5 g/mol; CAS number 909910-43-6. Visit STEMCELL.com for more information and related products.
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Selleck Chemical LLC PX-478 2HCl
PX-478 2HCl is an orally active and selective hypoxia-inducible factor-1 (HIF-1 ) inhibitor PX-478 2HCl induces apoptosis and has anti-tumor activity Phase 1
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Selleck Chemical LLC Galloflavin S9606-5MG
Galloflavin (NSC 107022) is a novel inhibitor of lactate dehydrogenasee (LDH) with Ki values of 5 46 M and 15 06 M for LDH-A and LDH-B respectively
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Selleck Chemical LLC MitoQ S8978-100MG
MitoQ (Mitoquinone) mesylate is a TPP-based mitochondria-targeted antioxidant that blocks H2O2-induced intracellular ROS responses and protects against oxidative damage This product is a waxy solid
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Selleck Chemical LLC Actinomycin D S8964-10MG
Actinomycin D (Dactinomycin Act D RASP-101) is a significant polypeptide antibiotic isolated from soil bacteria of the genus Streptomyces Actinomycin D (Dactinomycin) inhibits DNA repair and rests the cell cycle at G1 phase with IC50 of 0 42 M and 0 4 nM respectively Actinomycin D is an autophagy activator induces p53-independent cell death and prolongs survival in high-risk chronic lymphocytic leukemia This product is a hazardous chemical (acute toxicity/flammable/skin corrosive) Please use it while wearing a protective face mask gloves and clothing
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Selleck Chemical LLC IKE S8877-100MG
IKE(Imidazole ketone erastin) is a potent selective and metabolically stable system xc inhibitor and inducer of ferroptosis
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Selleck Chemical LLC XL177A S8967-10MM/1ML
XL177A is a potent selective and irreversible inhibitor of Ubiquitin specific peptidase 7 (USP7) with IC50 of 0 34 nM
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Selleck Chemical LLC Camizestrant S8958-10MM/1ML
Camizestrant (AZD9833) is an orally available and selective estrogen receptor (ER) antagonist with antineoplastic activity
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Selleck Chemical LLC BI-3812 S8735-5MG
BI-3812 is a highly potent and efficacious BCL6 inhibitor probe compound with an IC50 less than 3 nM
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